In-parallel artificial lung attachment at high flows in normal and pulmonary hypertension models.

Begum Akay, Junewai L. Reoma, Daniele Camboni, Joshua R. Pohlmann, John M. Albert, Ayushi Kawatra, Ayanna D Gouch, Robert H. Bartlett & Keith Cook
BACKGROUND: End-stage lung disease patients who require a thoracic artificial lung (TAL) must be extubated and rehabilitated prior to lung transplantation. The purpose of this study is to evaluate hemodynamics and TAL function under simulated rest and exercise conditions in normal and pulmonary hypertension sheep models. METHODS: The TAL, the MC3 Biolung (MC3, Inc, Ann Arbor, MI), was attached between the pulmonary artery and left atrium in nine normal sheep and eight sheep with chronic...
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