Deep Sleep, Cognition, Body Weight, Body Temperature, and Behavioral Distress Responses to New Onset Psychosocial Stressors are Blunted with Age in Male F344 Rats

Kendra E. Hargis
Complaints associated with aging, including cognitive deficits and sleep loss, are highly prevalent and negatively impact quality of life. Further, with increased age, humans are also more likely to experience new-onset psychosocial stressors, such as divorce, loss of a spouse, and social isolation. Stress has detrimental consequences that in many ways parallel the effects of aging on sleep and cognition. The long-standing stress/ glucocorticoid hypotheses of brain aging posit that stress exposure exacerbates aging symptoms,...
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