DEVELOPMENT OF A ROBUST LINAC-BASED RADIOSURGERY PROGRAM FOR MULTIPLE BRAIN METASTASES & ESTIMATION THE RADIOBIOLOGICAL RESPONSE OF INDIRECT CELL KILL

Allison Palmiero
Accurate and precise delivery of Stereotactic Radiosurgery (SRS) using Gamma Knife (GK) unit by Leksell is a gold standard for multiple intracranial lesions. SRS provides less brain toxicity compared to whole brain radiotherapy techniques historically used. However, these treatments are limited in availability and are accompanied by long treatment times with painful, intolerable headframe fixation. With advancements in linear accelerator (Linac) based SRS, multiple brain lesions can be treated separately with individual isocenters or, more...
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