DESIGN, SYNTHESIS, AND ANTICANCER PROPERTIES OF Ru(II) COMPLEXES WITH ORGANOMETALLIC, “EXPANDED” BIPYRIDINE, AND O,O’-CHELATING LIGANDS

Raphael Ryan
Cancer is a worldwide public health crisis that requires new and improved drugs to be developed to extend survival rates and improve quality of life for the patient. Platinum-based drugs are used in approximately 50% of cancer treatment regimens. These drugs are highly effective in many kinds of cancer; however, cancers can develop platinum resistance and these drugs have troubling side effects that reduced their use and efficacy. To overcome these disadvantages, many other metals...
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