Robust RNA Integrity-to-Neuronal Gene Expression Association in Autopsy Brain Tissue Not Explained by Post-Mortem Variables; and Acute Behavioral Stress Does Not Alter RNA Quality, While Progesterone Protects Against Effects of Stress Exposure

Eleanor Johnson
Transcriptional profiling (TP) is a common tool to determine RNA expression levels. It allows for thousands of genes to be analyzed simultaneously, and determines differences in gene expression levels due to various pathologies. RNA quality also impacts the reported expression level. One of the most common approaches for assessing RNA quality is Agilent Technology’s RNA integrity number (RIN). The use of RINs allowed scientists to standardize the assessment and reporting of RNA quality by predominantly...
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