Response to Valsalva Maneuver in Humans

Samuel A. Kosinski, Brian E. Carlson, Scott L. Hummel, Robert D. Brook & Daniel A. Beard
Functional metrics of autonomic control of heart rate, including baroreflex sensitivity, have been shown to be strongly associated with cardiovascular risk. A decrease in baroreflex sensitivity with aging is hypothesized to represent a contributing causal factor in the etiology of primary hypertension. To assess baroreflex function in human subjects, two complementary methods to simulate the response in heart rate elicited by the Valsalva maneuver were developed and applied to data obtained from a cohort of...
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