Expression of TLR7 in the murine eye during the embryonic period and in the adult animal

Isabella Barajon, Marco Rasile, Francesca Arnaboldi & Alessandra Menon
In the present study, we evaluated Toll-like receptor 7 (TLR7) expression at different stages of the murine eye development and in the adult organ. In mammals, TLRs are best known for their immunitary function, however data from the literature are demonstrating that in analogy to their Drosophila homologue Toll, they also participate in developmental mechanisms (Okun, Griffioen and Mattson 2011, Shechter et al. 2008). Immunohistochemistry for TLR7 and double immunofluorescence for TLR7/PCNA were performed on...
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