In vivo biodegradation of a new PVP-Hydrogel

Paola Coppa, Maria A. Continenza, Elena Di Marco, Leonardo A. Pajewski & Francesco Vegliò
The target applications of the hydrogel biomaterials are the “difficult wounds”, that is the wounds caused by burns, abrasions and ulcerations, by vascular or endocrine disorders (diabetes). This study describes the in vivo biodegradation process of a new biomaterial (PVP-Hydrogel), comparing it with a haemostatic biomaterial (Matemo) which had showed a complete biodegradation process in previous experiments. The new hydrogel consists of three biocompatible polymers: Polyvinyl pyrrolidone (PVP), Agar and Polyethylene glycol (PEG), at first...
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