Ultrastructural modifications of myotendinous junction with disuse

Davide Curzi, Sabrina Burattini, James G. Tidball & Elisabetta Falcieri
The skeletal muscle contraction is transmitted to the tendon through the myotendinous junction (MTJ), where the proximal extremity of tendon forms characteristic finger-like processes, penetrating into the muscle mass (Ciena et al., 2010). MTJ represents an intriguing and complex structure from both biological and functional point of view. We recently demonstrated that changes at MTJ level occur as an adaptation to exercise-induced tension increase. In particular, branching of finger-like processes increases, so enlarging the whole...
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