Osteogenic differentiation of MG63 cells in biodegradable scaffolds based on gelatin and genipin

Sandra Durante, Adriana Bigi, Milena Fini, Antonio Mazzotti, Roberto Giardino & Gabriella Teti
Gelatin is a denatured collagen and commercially available as a biodegradable polymer. It has been extensively utilized for pharmaceutical and medical purposes, and its biosafety has been proven through long clinical applications. It showed an high cell attachment and proliferation, thus it has been widely considered as one of the best material to be used in medicine regenerative. Scaffolds based on pure gelatin showed a low mechanical and biological stability, so that a chemical crosslinking...
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