Vascular cell dysfunctions: a possible atheroprotective role of melatonin

Gaia Favero, Stefania Castrezzati, Marco Ferrari, Francesco Belotti, Alessandra Stacchiotti & Luigi Fabrizio Rodella
Atherosclerosis is a chronic disease of the arterial wall and a leading cause of death and loss of productive life years worldwide. It is considered a chronic inflammatory vascular disease characterized of monocyte extravasation into the arterial wall (Libby et al., 2011). Researches into the disease have led to many compelling hypotheses about the pathophysiology of atherosclerotic lesion formation and of complications such as myocardial infarction and stroke (Ross, 1999). The last several decades have...
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