Centrosome: is it a geometric, noise resistant, 3D interface that translates morphogenetic signals into precise locations in the cell?

Marco F. Regolini
The requirements of a spherical reference system based on two orthogonal goniometers show a surprising correspondence with the evidence emerging from numerous experimental studies on centrioles and centrosomes: the centrosome, because of the 9-fold symmetry of its centrioles, their orthogonal arrangement and their circumferential polarity, may play the role of an interface, composed by two orthogonal goniometers, that recognizes and decodes morphogenetic instructions, or, more generally, geometric molecular signals and translates them into their expected...
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