Use of chitosan scaffolds for repairing rat sciatic nerve defects

Maria J. Simões, Sandra Amado, Andrea Gärtner, Paulo A.S. Armada-Da-Silva, Stefania Raimondo, Marcia Vieira, Ana L. Luís, Yuki Shirosaki, António P. Veloso, José D. Santos, Artur S.P. Varejão, Stefano Geuna & Ana C. Maurício
Neurotmesis must be surgically treated by direct end-to-end suture of the two nerve stumps or by a nerve graft harvested from elsewhere in the body in case of tissue loss. To avoid secondary damage due to harvesting of the nerve graft, a tube-guide can be used to bridge the nerve gap. Previously, our group developed and tested hybrid chitosan membranes for peripheral nerve tubulization and showed that freeze-dried chitosan type III membranes were particularly effective...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.