Modeling macronuclear DNA regulation in two ciliates : Paramecium tetraurelia and Tetrahymena thermophila

Cassandra Elphinstone & Kyle Cheadle
A revision to existing models for regulating the macronuclear DNA content of the ciliates Paramecium tetraurelia and Tetrahymena thermophila explains previously unresolved observations. Using an independent parameter to regulate ciliate macronuclear DNA content allows the mass of P. tetraurelia to be linked with DNA regulation. A similar parameterization of the T. thermophila model accounts for observed generation-dependent variations. Introducing controlled selection rules on macronuclear DNA content in modeled populations of T. thermophila results in evolving...
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