Favorable longitudinal change of lung function in patients with asthma-COPD overlap from a COPD cohort

Hye Y Park, Suh-Young Lee, Danbee Kang, Juhee Cho, Hyun Lee, Seong Y Lim, Ho I Yoon, Seung W Ra, Ki U Kim, Yeon-Mok Oh, Don D Sin, Sang-Do Lee & Yong B Park
Background: The recognition of asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) as a distinct phenotype of COPD or asthma has increased. Although ACO has worse clinical features than non-ACO COPD, limited information is available on long-term outcomes of lung function decline for ACO and non-ACO COPD. Methods: COPD patients with at least 3 years of follow-up were selected from the Korean Obstructive Lung Disease cohort. ACO was defined based on 3 major criteria: 1) airflow...
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