Case report: Successful induction of buprenorphine/naloxone using a microdosing schedule and assertive outreach

Jennifer Rozylo, Keren Mitchell, Mohammadali Nikoo, S. E Durante, Skye P Barbic, Daniel Lin, Steve Mathias & Pouya Azar
Background: The requirement for moderate withdrawal prior to initiation can be a barrier to buprenorphine/naloxone induction. Case presentation: We aimed to use a microdosing regimen to initiate regular dosing of buprenorphine/naloxone in a high-risk patient with a history of failed initiations due, in part, to withdrawal symptoms. Using an assertive outreach model and a buprenorphine/naloxone microdosing schedule, we initiated treatment of an individual’s opioid use disorder. There was a successful buprenorphine/naloxone microdosing induction as the...
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