The gut is exposed constantly to invading bacterial populations and dietary antigens. To protect it from harm, a complex and diverse network of patrolling immune cells can be found spread throughout the gut and in specialized lymphoid structures. One immune cells type playing a key role in the protection and homeostasis of the gut, are the intraepithelial T-lymphocytes (IELs). This population of T cells, reside within the epithelial layer of the gut and are primarily...