Raw diffraction images for apo murine Fumarylacetoacetate Domain Containing Protein 1 (FAHD1)

Alexander Weiss, Andreas Naschberger, Elia Cappuccio, Matthew Bowler, Jill Von Velsen, Bernhard Rupp & Pidder Jansen-Dürr
FAH domain-containing protein 1 (FAHD1) is a mitochondrial protein displaying both acylpyruvate hydrolase (ApH) and oxaloacetate decarboxylase (ODx) activity. As mitochondrial ODx, FAHD1 acts antagonistically to pyruvate carboxylase, a key metabolic enzyme. Despite its importance for mitochondrial function, very little is known about the catalytic mechanisms underlying FAHD1 enzymatic activities, and the architecture of its ligated active site is currently ill defined. These data are for the mouse protein. The structural basis for the bi-functionally...
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