A genome-wide study of two-component signal transduction systems in eight newly sequenced mutans streptococci strains

Lifu Song, Padhmanand Sudhakar, Wei Wang, Georg Conrads, Anke Brock, Jibin Sun, Irene Wagner-Döbler & An-Ping Zeng
Mutans streptococci are a group of gram-positive bacteria including the primary cariogenic dental pathogen Streptococcus mutans and closely related species. Two component systems (TCSs) composed of a signal sensing histidine kinase (HK) and a response regulator (RR) play key roles in pathogenicity, but have not been comparatively studied for these oral bacterial pathogens.
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