Computational model of gastric motility with active-strain electromechanics

Sebastian Brandstäter, Alessio Gizzi, Sebastian L. Fuchs, Amadeus M. Gebauer, Roland Aydin & Christian J. Cyron
We present an electro-mechanical constitutive framework for the modeling of gastric motility, including pacemaker electrophysiology and smooth muscle contractility. In this framework, we adopt a phenomenological description of the gastric tissue. Tissue electrophysiology is represented by a set of two minimal two-variable models and tissue electromechanics by an active-strain finite elasticity approach. We numerically investigate the implication of the spatial distribution of pacemaker cells on the entrainment and synchronization of the slow waves characterizing gastric...