Functional characterization of the inverse FBAR-containing proteins srGAP1 and Carom

Anitha Jeyanthan
The Slit-Robo GTPase activating protein family (srGAPs) consists of four members and are important multi-domain adaptor proteins, which are involved in axonal pathfinding and various other neuronal processes. This thesis explores the function of the human srGAP1 protein as well as its zebrafish homolog in three ways: 1) examining of the membrane deforming activity of the FBAR domain, 2) analysing the specific activity of the srGAP1 GAP domain towards three members of RhoGTPases, and 3)...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.