Assessing Ciclosporin in the Treatment of Leprosy Reactions: Evidence from a Randomized Controlled Trial and Other Studies.

SM Lambert
Leprosy patients present with a spectrum of skin lesions and neuropathy. Despite multi-drug therapy (MDT), which cures the infection, immunological reactions continue to occur, leading to disability and deformity secondary to neuropathy. Reactions are a major cause of morbidity and long term disability. The treatment of reactions is currently inadequate, with prednisolone being the main drug used with partial success and a high rate of side effects. Identifying better agents for treating leprosy reactions is...
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