Anacardium microcarpum extract and fractions protect against paraquat-induced toxicity in Drosophila melanogaster

Katiane Raquel Müller, Illana Kemmerich Martins, Nathane Rosa Rodrigues, Litiele Cezar Da Cruz, Valter Menezes Barbosa Filho, Giulianna Echeverria Macedo, Gustavo Felipe Da Silva, Jean Paul Kamdem, Irwin Rose Alencar De Menezes, Jeferson Luis Franco & Thaís Posser
Anacardium microcarpum Ducke (Anacardiaceae) is a native species of Brazil used in folk medicine for the treatment of several illnesses although its antioxidant activity has been reported in vitro, there is no evidence of this effect in an in vivo model. Here, we investigated the potential protective effect of hydroalcoholic extract (AMHE), methanol (AMMF) and acetate (AMAF) fraction of A. microcarpum against paraquat toxicity on survivorship, locomotor performance, antioxidant enzymes activity and reactive species using...
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