Downregulation of Sirt1 is correlated to upregulation of p53 and increased apoptosis in epicardial adipose tissue of patients with coronary artery disease

Mahdieh Khanahmadi, Babak Manafi, Heidar Tayebinia, Jamshid Karimi & Iraj Khodadadi
The higher expression level of p53 in epithelial adipose tissue (EAT) has previously been reported in atherosclerosis. Since we hypothesized that the expression of p53 is modulated by Sirt1, the aim of this study was to determine the expression levels of Sirt1 and p53 and to investigate their correlation to apoptosis in EAT of patients with coronary artery disease (CAD). Thirty-five patients with more than 50 % stenosis in at least one of the main...
1 citation reported since publication in 2020.
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.