Reactivation-dependent amnesia for contextual fear memories in rodents: Assessment of publication bias

Natalie Schroyens, Eric Sigwald, Wim Van Den Noortgate, Tom Beckers & Laura Luyten
Research on memory reconsolidation has been booming in the last two decades, with numerous high-impact publications reporting promising amnestic interventions in rodents and humans. However, our own recently- published failed replication attempts of reactivation-dependent amnesia for fear memories in rats suggest that such amnestic effects are not always readily found and that they depend on subtle and possibly uncontrollable parameters. The discrepancy between our observations and published studies in rodents suggests that the literature in...
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