Cortical Thickness and Resting State Cardiac Function Across the Lifespan: A Cross-Sectional Pooled Mega Analysis

Julian Koenig, Birgit Abler, Ingrid Agartz, Torbjörn Åkerstedt, Ole Andreassen, Mia Anthony, Katja Bertsch, Rebecca Brown, Romuald Brunner, Luca Carnevali, Hugo Critchley, Kathryn Cullen, Eco de Geus, Isabel Dziobek, Håkan Fischer, Herta Flor, Michael Gaebler, Peter Gianaros, Melita Giummarra, Steven Greening, Simon Guendelman, James Heathers, Sabine Herpertz, Mandy Hu, Sebastian Jentschke … & HYUN YOO
Resting state autonomic nervous system activity [ANS] indexed by measures of heart rate [HR] and its variability [HRV], is associated with brain morphology, in particular cortical thickness [CT]. However, findings have been mixed regarding the regions of interest [ROI] associated with HR/HRV and the direction of the association. Sex and age differences in HR/HRV and CT may explain some of the existing inconsistencies. Understanding the association between ANS function and brain morphology across aging, may...
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