Neutrophil rheology and transit through capillaries and sinusoids

In normal lungs, the concentration of neutrophils within the pulmonary capillary blood is about 40–80 times higher than it is within the blood in large vessels (1). This increased concentration, often referred to as the marginated pool, is thought to play an important role in host defense by allowing neutrophils time to sniff the local environment, looking for evidence of organisms or other stimuli that have escaped the initial barriers of host defense. The increased...
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