In vitro characterisation of the neutrophil in respiratory syncytial virus bronchiolitis

Gemma Saint
Background: Respiratory Syncytial Virus (RSV) is a common cause of bronchiolitis during infancy; virtually all children are infected with this virus by the age of 2 years. Although the majority have a self-limiting, mild infection, 1- 3% have disease severe enough to warrant hospital admission. These children have an abundance of neutrophils (>80% of bronchoalveolar lavage cells) within their airways. There is however, a lack of detailed investigation into their role in viral infection. Our...
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