Factors which influence penetrance in Familial Pancreatic Cancer

JV Butler
Introduction Pancreatic cancer (PDAC) confers a high mortality rate as it often presents at an advanced stage. Screening could improve early detection and survival. However, the prevalence of the disease and absence of specific screening tools mean that screening of the general population would result in many false positive tests. This may mean unnecessary overtreatment including surgery with considerable morbidity. Current screening techniques have associated risks including exposure to radiation and induction of pancreatitis. It...
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