The Role of the Deubiquitylase UCHL3 During Alphavirus Infection

SC King
Alphaviruses are positive-sense RNA viruses from the family Togaviridae. These viruses rely on arthropod vectors, such as mosquitos, to replicate before transmission to vertebrates. There are several medically important viruses in this group, including Chikungunya virus (CHIKV) which, since 2004, has caused large number of epidemics that have infected millions of people in Asia, the Indian subcontinent, Europe, the Americas and the Pacific Islands. Consequences of CHIKV infection can include chronic and debilitating arthritis and,...
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