Landscape genetics of Anopheles gambiae in southern Ghana

John Essandoh
Insecticide application via indoor residual spraying (IRS) and long-lasting insecticide-treated bednets (LLIN) has been a key component in combating malaria in sub-Saharan Africa, with pyrethroids being the traditionally recommended insecticides. However, the resistance of Anopheles gambiae s.s. and An. coluzzii to pyrethroids is high and widespread, especially in West Africa, underpinned in part by high frequencies of the L1014F target-site mutation in the voltage-gated sodium channel (Vgsc). Carbamate (CB) and organophosphate (OP) resistance is generally...
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