Risk prediction models for colorectal cancer in people with symptoms: a systematic review

Tom G S Williams, Joaquín Cubiella, Simon J Griffin, Fiona M Walter & Juliet A Usher-Smith
Abstract Background Colorectal cancer (CRC) is the fourth leading cause of cancer-related death in Europe and the United States. Detecting the disease at an early stage improves outcomes. Risk prediction models which combine multiple risk factors and symptoms have the potential to improve timely diagnosis. The aim of this review is to systematically identify and compare the performance of models that predict the risk of primary CRC among symptomatic individuals. Methods We searched Medline and...
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