Association of puberty timing with type 2 diabetes: A systematic review and meta-analysis.

Tuck Seng Cheng, Felix R Day, Rajalakshmi Lakshman & Ken K Ong
BACKGROUND:Emerging studies have investigated the association between puberty timing, particularly age at menarche (AAM), and type 2 diabetes. However, whether this association is independent of adiposity is unclear. We aimed to systematically review published evidence on the association between puberty timing and type 2 diabetes (T2D) or impaired glucose tolerance (IGT), with and without adjustment for adiposity, and to estimate the potential contribution of puberty timing to the burden of T2D in the United Kingdom...
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