Central disorders of thyroid function: clinical, radiological and genetic phenotyping

Olympia Koulouri
In the last 50 years there have been great advances in the field of central thyroid disorders. However, despite important developments, such as the introduction of ultrasensitive TSH assays and improvements in pituitary imaging studies, diagnosing and uncovering the aetiology of both central hyper- and hypo-thyroidism remains challenging in many cases. This thesis adds data to the existing literature generated from studies in large cohorts of patients with TSH secreting pituitary tumours (TSHoma) and describes...
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