Supramolecular catalysis by recognition-encoded oligomers: Discovery of a synthetic imine polymerase

L Gabrielli & Christopher Hunter
All key chemical transformations in biology are catalysed by linear oligomers. Catalytic properties could be programmed into synthetic oligomers in the same way as they are programmed into proteins, and an example of the discovery of emergent catalytic properties in a synthetic oligomer is reported. Dynamic combinatorial chemistry experiments designed to study the templating of a recognition-encoded oligomer by the complementary sequence have uncovered an unexpected imine polymerase activity. Libraries of equilibrating imines were formed...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.