Detection of Rare Antimicrobial Resistance Profiles by Active and Passive Surveillance Approaches

Alison Mather, Richard Reeve, Dominic J Mellor, Louise Matthews, Richard J Reid-Smith, Lucie Dutil, Daniel T Haydon & Stuart WJ Reid
Antimicrobial resistance (AMR) surveillance systems are generally not specifically designed to detect emerging resistances and usually focus primarily on resistance to individual drugs. Evaluating the diversity of resistance, using ecological metrics, allows the assessment of sampling protocols with regard to the detection of rare phenotypes, comprising combinations of resistances. Surveillance data of phenotypic AMR of Canadian poultry $\textit{Salmonella}$ Heidelberg and swine $\textit{Salmonella}$ Typhimurium var. 5- were used to contrast active (representative isolates derived from healthy...
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