Determining gene expression control during neural differentiation through coupled protein localization and RNA-seq in single cells

Sarah Hainer
Although the primary sequence of the eukaryotic genome is largely invariant across cells in an organism, the expression of genes is tightly regulated: specific complements and levels of expressed genes define the identity and function of cells. A primary mechanism of gene expression control is at the level of access to DNA sequences that can direct expression of individual genes. Access to these DNA regulatory elements is established and maintained by the combinatorial binding of...
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