Posttranscriptional gene regulation in enterohemorrhagic Escherichia coli O157:H7

Amber Sauder
Bacteria must sense and respond to environmental cues to survive and replicate in diverse environments. Tight regulation of metabolic and virulence gene expression is required for pathogens to compete with the host microbiota, replicate, and subvert the immune system. The foodborne pathogen enterohemorrhagic Escherichia coli O157:H7 (EHEC) has a very low infectious dose, indicating successful adaptation to the various environments in the gastrointestinal (GI) tract. Whereas the role of transcriptional regulators in EHEC niche adaptation...
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