Form and Function Relationships Governing Complex Muscle-Soft Tissue Interactions Revealed with 3D Modeling: Applications to Aging

Katherine Knaus
The universal experience of aging presents many clinical problems rooted in muscle dysfunction. Muscles actuate movement required for daily life and understanding muscle function prior to the onset of age-related changes is critical in addressing these problems. Muscle function depends on both its fiber architecture (the arrangement of its cells) and its interaction with elastic connective tissues. When muscles have complex architectures and connective tissue interfaces it is difficult to intuit the full relationship between...
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