A Computational Model Driven Design of a Novel Therapeutic Strategy for Targeting Klebsiella pneumoniae; The Causes and Implications of the Overuse of Antibiotics in Healthcare

Mary Dickenson
In recent years, strains of infectious bacteria have evolved to become increasingly more resistant to the drugs commonly used to treat them, culminating in around 3 million drug-resistant infections in the United States each year. By far the most common cause of these infections is the bacterial pathogen Klebsiella pneumoniae. With the vast majority of K. pneumoniae clinical strains now demonstrating a wide range of resistance to antibiotics, almost all available medications have been rendered...
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