Regulation and Function of the Nuclear Transport Factor KPNA7

Luke Oostdyk
Genetic material in eukaryotic cells is isolated inside the double membrane of the nucleus. To facilitate the myriad processes which occur within, cells need a mechanism to transport important nuclear proteins through the semipermeable pore complexes of the nuclear membrane. While multiple transport pathways exist, the best characterized relies on a short amino acid sequence termed a nuclear localization signal (NLS). These signals are diverse but typically consist of one or two clusters of basic...
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