Phagocytic Communication During Apoptotic Cell Clearance and Inflammation

Claudia Han
Clearance of apoptotic cells is essential for tissue homeostasis, development and inflammation resolution; it is carried out by professional phagocytes, such as macrophages, and non-professional phagocytes, such as epithelial cells. In most tissues, such as the lung and the brain, professional and non-professional phagocytes reside in close proximity, but it is not known how they co-regulate the cell clearance process. This thesis research has revealed that macrophages redirect the phagocytosis of epithelial cells and this...
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