Neural Control of Respiration by the Retrotrapezoid Nucleus.

Tyler Basting
Rationale and objectives: Central respiratory chemoreceptors (CRCs) detect brain PaCO2 and adjust lung ventilation to maintain PaCO2 and pH constant regardless of the absolute level of lung ventilation. They perform this function in cooperation with the carotid bodies, sensory organs that respond to hypoxia in a pH-dependent manner. The existence of CRCs has been known for over a century but their cellular nature and location have remained highly controversial until recently. The retrotrapezoid nucleus (RTN),...
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