Sphingolipids and Prostate Cancer: complex molecules for a complex disease

Pedro Filipe Da Costa Pinheiro
Prostate cancer (PCa) is the second most incident cancer in men worldwide, and despite vast amounts of research it remains one of the major epidemiological burdens in oncology. The prostate gland is regulated by male androgens that activate the Androgen Receptor (AR), a transcription factor and a master regulator of several different signaling pathways, contributing towards normal development of the organ. In PCa, these hormones exert an important role in the onset and progression of...
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