Leveraging Proteomic Strategies to Analyze Post-Translational Modifications and Membrane Proteins

Maria Panepinto
This dissertation details three projects that apply tandem mass spectrometry to analyze purified proteins. There are three strategies that can be used to approach proteomic analysis: intact, limited digestion, and traditional digestion. All three of these projects are unified in that at least two of these strategies was required to achieve their goal. This dissertation demonstrates that these approaches are much more powerful and provide more information in combination than they do alone. The first...
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