Trans-epithelial transport of Maillard reaction products (MRPs) through the GLUT receptor in a Caco-2 cell line

Abhishek Bhattacherjee, Yuliya Hrynets & Mirko Betti
Dietary MRPS represent a diverse class of molecules, and their impact on human health is a matter of debate. A prerequisite for a physiological effect from dietary MRPs is that they are transported across the intestinal barrier. The objective of this study was to demonstrate a possible mechanism for MRPs transport in a human intestinal cell line (Caco-2). To produce the MRPs, a tripeptide Lys-Pro-Hyp was synthesized and non-enzymatically glycated with glucose. MRPs [Amadori peptide...
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