Development of acetylcholinesterase biosensors for neurotoxins detection in foods and the environment

Clarisse Brüning Schmitt Roepcke
Acetylcholinesterase (AChE) is responsible for the hydrolysis of acetylcholine in the nervous system. It is inhibited by several substances, like organophosphate and carbamate insecticides, glycoalkaloids, nerve gas and anatoxin-a(s). There is a growing need to develop new technologies to reduce time spent with sample preparation, discriminate between positive and negative samples, and to reduce analysis costs. Over the last decades, AChE biosensors have emerged as an ultra sensitive and rapid technique for toxicity analysis in...
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