Intercellular communication in three-dimensional culture

Dieter F. Hülser
The coordination of cell growth and differentiation as well as of tissue homeostasis and synchronization of tissue functions requires the transfer of information between cells. This may be achieved by an unidirectional signal flow, as is the case with secreted molecules (hormones. neurotransmitters) and or with membrane-bound receptors (sperm-egg binding, immune system). It can also follow a nonrectifying mode. as is observed for direct intercellular communication via gap junctions that are founed in regions of...
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