Approaching clinical proteomics: current state and future fields of application in fluid proteomics

Rolf Apweiler, Charalampos Aslanidis, Thomas Deufel, Andreas Gerstner, Jens Hansen, Dennis Hochstrasser, Roland Kellner, Markus Kubicek, Friedrich Lottspeich, Edmund Maser, Hans-Werner Mewes, Helmut E. Meyer, Stefan Müllner, Wolfgang Mutter, Michael Neumaier, Peter Nollau, Hans G. Nothwang, Fredrik Ponten, Andreas Radbruch, Knut Reinert, Gregor Rothe, Hannes Stockinger, Attila Tarnok, Mike J. Taussig, Andreas Thiel … & Gerd Schmitz
The field of clinical proteomics offers opportunities to identify new disease biomarkers in body fluids, cells and tissues. These biomarkers can be used in clinical applications for diagnosis, stratification of patients for specific treatment, or therapy monitoring. New protein array formats and improved spectrometry technologies have brought these analyses to a level with potential for use in clinical diagnostics. The nature of the human body fluid proteome with its large dynamic range of protein concentrations...
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