Unstimulated high sensitive thyroglobulin measurement predicts outcome of differentiated thyroid carcinoma

Luca Giovanella, Marco Maffioli, Luca Ceriani, Diego De Palma & Giuseppe Spriano
Background: Thyroglobulin (Tg) measurement following thyrotropin (TSH) stimulation is used in the follow-up of patients with differentiated thyroid carcinoma (DTC). However, high-sensitive assays allow accurate measurement of serum Tg even without TSH stimulation. Here, we prospectively evaluated the impact of unstimulated high-sensitive Tg measurement in early and long-term outcome of patients with DTC. Methods: One hundred and ninety five patients affected with DTC were evaluated. Six months after thyroid ablation (i.e., thyroidectomy plus radioiodine) serum...
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